Structure of the human cation-independent mannose 6-phosphate/IGF2 receptor domains 7–11 uncovers the mannose 6-phosphate binding site of domain 9

Structure of the human cation-independent mannose 6-phosphate/IGF2 receptor domains 7–11 uncovers the mannose 6-phosphate binding site of domain 9

The cation-independent mannose 6-phosphate (M6P)/Insulin-like growth factor-2 receptor (CI-MPR/IGF2R) is an ∼300 kDa transmembrane protein responsible for trafficking M6P-tagged lysosomal hydrolases and internalizing IGF2. The extracellular region of the CI-MPR has 15 homologous domains, including M...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän:	Bochel, AJ, Williams, C, McCoy, AJ, Hoppe, H-J, Winter, AJ, Nicholls, RD, Harlos, K, Jones, EY, Berger, I, Hassan, AB, Crump, MP
Materialtyp:	Journal article
Språk:	English
Publicerad:	Cell Press 2020

Liknande verk

Tissue plasminogen activator is a ligand of cation-independent mannose 6-phosphate receptor and consists of glycoforms that contain mannose 6-phosphate
av: James J. Miller, et al.
Publicerad: (2021-04-01)

Interactions of IGF-II with the IGF2R/cation-independent mannose-6-phosphate receptor mechanism and biological outcomes.
av: Brown, J, et al.
Publicerad: (2009)

The host mannose-6-phosphate pathway and viral infection
av: Qincheng Liu, et al.
Publicerad: (2024-01-01)

Gold Nanoparticles Decorated with Mannose-6-phosphate Analogues
av: Stéphanie Combemale, et al.
Publicerad: (2014-01-01)

In vitro binding of HFE to the cation-independent mannose-6 phosphate receptor.
av: Schimanski, L, et al.
Publicerad: (2009)

Kinetics of insulin-like growth factor II (IGF-II) interaction with domain 11 of the human IGF-II/mannose 6-phosphate receptor: function of CD and AB loop solvent-exposed residues.
av: Zaccheo, O, et al.
Publicerad: (2006)

Real time kinetics of insulin-like growth factor II (IGF-II) interaction with the IGF-II/mannose 6-phosphate receptor: the effects of domain 13 and pH.
av: Linnell, J, et al.
Publicerad: (2001)

The effect of Mannose-6-Phosphate on recovery after sciatic nerve repair
av: Ngeow, W.C., et al.
Publicerad: (2011)

The effect of Mannose-6-Phosphate on recovery after sciatic nerve repair
av: Ngeow, Wei Cheong, et al.
Publicerad: (2011)

Synthesis of C6-modified mannose 1-phosphates and evaluation of derived sugar nucleotides against GDP-mannose dehydrogenase
av: Sanaz Ahmadipour, et al.
Publicerad: (2022-09-01)

Characterization of a Mannose-6-Phosphate Isomerase from Bacillus amyloliquefaciens and Its Application in Fructose-6-Phosphate Production.
av: Sujan Sigdel, et al.
Publicerad: (2015-01-01)

A novel binding site for the human insulin-like growth factor-II (IGF-II)/mannose 6-phosphate receptor on IGF-II.
av: Delaine, C, et al.
Publicerad: (2007)

Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease.
av: Carmela Matrone, et al.
Publicerad: (2016-01-01)

Surface plasmon resonance analysis of complex formation of therapeutic recombinant lysosomal enzymes with domain 9 of human cation-independent mannose 6-phosphate receptor
av: Minori Kanzaki, et al.
Publicerad: (2020-12-01)

Lysosome sorting of β-glucocerebrosidase by LIMP-2 is targeted by the mannose 6-phosphate receptor
av: Zhao, Y, et al.
Publicerad: (2014)

GCAF(TMEM251) regulates lysosome biogenesis by activating the mannose-6-phosphate pathway
av: Weichao Zhang, et al.
Publicerad: (2022-09-01)

Keys to the hidden treasures of the mannose 6-phosphate/insulin-like growth factor 2 receptor.
av: Hassan, A
Publicerad: (2003)

Targeted protein degradation through site-specific antibody conjugation with mannose 6-phosphate glycan
av: Kaori Mukai, et al.
Publicerad: (2024-12-01)

Engineered therapeutic antibodies with mannose 6-phosphate analogues as a tool to degrade extracellular proteins
av: Morgane Daurat, et al.
Publicerad: (2024-03-01)

Mannose 6-phosphate receptors, Niemann-Pick C2 protein, and lysosomal cholesterol accumulation
av: Marion Willenborg, et al.
Publicerad: (2005-12-01)

Clinical outcomes in an adult patient with mannose phosphate isomerase-congenital disorder of glycosylation who discontinued mannose therapy
av: Kinza Noman, et al.
Publicerad: (2020-12-01)

Enzymatic synthesis of mannosyl retinyl phosphate from retinyl phosphate and guanosine diphosphate mannose
av: G.C. Rosso, et al.
Publicerad: (1975-05-01)

What contributes to an effective mannose recognition domain?
av: Christoph P. Sager, et al.
Publicerad: (2017-12-01)

ZIP10 is a negative determinant for anti-tumor effect of mannose in thyroid cancer by activating phosphate mannose isomerase
av: Sharui Ma, et al.
Publicerad: (2021-12-01)

Chlamydia interfere with an interaction between the mannose-6-phosphate receptor and sorting nexins to counteract host restriction
av: Cherilyn A Elwell, et al.
Publicerad: (2017-03-01)

Lysosomal enzymes and mannose 6-phosphate receptors in the lacrimal drainage system: Evidence and its potential implications
av: Mohammad Javed Ali, et al.
Publicerad: (2018-01-01)

Human immunodeficiency virus-1 uses the mannose-6-phosphate receptor to cross the blood-brain barrier.
av: Shinya Dohgu, et al.
Publicerad: (2012-01-01)

Mannose 6-phosphate receptor and sortilin mediated endocytosis of α-galactosidase A in kidney endothelial cells.
av: Thaneas Prabakaran, et al.
Publicerad: (2012-01-01)

Lysosomal enzyme binding to the cation-independent mannose 6-phosphate receptor is regulated allosterically by insulin-like growth factor 2
av: Richard N. Bohnsack, et al.
Publicerad: (2024-11-01)

Mannose phosphate isomerase-congenital disorder of glycosylation leads to asymptomatic hypoglycemia
av: Cheng Luo, et al.
Publicerad: (2024-12-01)

Gene Cloning of Iranian Leishmania major Mannose-1-Phosphate Guanyltransferase
av: SH Hejazi, et al.
Publicerad: (2009-09-01)

Gene Cloning of Iranian Leishmania major Mannose-1-Phosphate Guanyltransferase
av: R Salehi, et al.
Publicerad: (2009-07-01)

A role of Rab29 in the integrity of the trans-Golgi network and retrograde trafficking of mannose-6-phosphate receptor.
av: Shicong Wang, et al.
Publicerad: (2014-01-01)

Structural model for the mannose receptor family uncovered by electron microscopy of Endo180 and the mannose receptor.
av: Boskovic, J, et al.
Publicerad: (2006)

Circulating levels of insulin-like growth factor-II/mannose-6-phosphate receptor in obesity and type 2 diabetes.
av: Jeyaratnaganthan, N, et al.
Publicerad: (2010)

Reduction of tendon adhesions following administration of Adaprev, a hypertonic solution of mannose-6-phosphate: mechanism of action studies.
av: Jason K F Wong, et al.
Publicerad: (2014-01-01)

Mannose-6-phosphate glycan for lysosomal targeting: various applications from enzyme replacement therapy to lysosome-targeting chimeras
av: Jinho Seo, et al.
Publicerad: (2022-05-01)

Involvement of sphingosine 1-phosphate signaling in insulin-like growth factor-II/mannose 6-phosphate receptor trafficking from endosome to the trans-Golgi network
av: Susumu Nishida, et al.
Publicerad: (2024-09-01)

Elevated mRNA expression and defective processing of cathepsin D in HeLa cells lacking the mannose 6‐phosphate pathway
av: Lin Liu, et al.
Publicerad: (2021-06-01)

Chemical synthesis of C6-tetrazole ᴅ-mannose building blocks and access to a bioisostere of mannuronic acid 1-phosphate
av: Eleni Dimitriou, et al.
Publicerad: (2021-07-01)