The impact of diabetes mellitus on coronary artery disease: new therapeutic approaches.
Patients with diabetes mellitus (DM) type 2 have a high prevalence of coronary artery disease (CAD), as diabetes is implicated in the formation of atherosclerotic plaque. Hyperglycemia, elevated free fatty acid, increased amount of circulating end-glucosylated serum products and insulin resistance a...
| Päätekijät: | , , , , , |
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| Aineistotyyppi: | Journal article |
| Kieli: | English |
| Julkaistu: |
2009
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| _version_ | 1826289315309682688 |
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| author | Tousoulis, D Kampoli, A Papageorgiou, N Papaoikonomou, S Antoniades, C Stefanadis, C |
| author_facet | Tousoulis, D Kampoli, A Papageorgiou, N Papaoikonomou, S Antoniades, C Stefanadis, C |
| author_sort | Tousoulis, D |
| collection | OXFORD |
| description | Patients with diabetes mellitus (DM) type 2 have a high prevalence of coronary artery disease (CAD), as diabetes is implicated in the formation of atherosclerotic plaque. Hyperglycemia, elevated free fatty acid, increased amount of circulating end-glucosylated serum products and insulin resistance are the main mechanisms involved in the accelerated atherosclerotic process observed in type 2 DM patients. Novel treatments have been proposed to prevent and treat CAD in patients with diabetes, mainly in those with diabetes type 2. Several clinical trials have been designed in order to examine the effectiveness of these agents, such as angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers, glitazones, statins and antioxidants, but the results are still controversial. |
| first_indexed | 2024-03-07T02:27:00Z |
| format | Journal article |
| id | oxford-uuid:a5f315f0-5701-44ec-8842-a3136e30f4c0 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:27:00Z |
| publishDate | 2009 |
| record_format | dspace |
| spelling | oxford-uuid:a5f315f0-5701-44ec-8842-a3136e30f4c02022-03-27T02:43:56ZThe impact of diabetes mellitus on coronary artery disease: new therapeutic approaches.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a5f315f0-5701-44ec-8842-a3136e30f4c0EnglishSymplectic Elements at Oxford2009Tousoulis, DKampoli, APapageorgiou, NPapaoikonomou, SAntoniades, CStefanadis, CPatients with diabetes mellitus (DM) type 2 have a high prevalence of coronary artery disease (CAD), as diabetes is implicated in the formation of atherosclerotic plaque. Hyperglycemia, elevated free fatty acid, increased amount of circulating end-glucosylated serum products and insulin resistance are the main mechanisms involved in the accelerated atherosclerotic process observed in type 2 DM patients. Novel treatments have been proposed to prevent and treat CAD in patients with diabetes, mainly in those with diabetes type 2. Several clinical trials have been designed in order to examine the effectiveness of these agents, such as angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers, glitazones, statins and antioxidants, but the results are still controversial. |
| spellingShingle | Tousoulis, D Kampoli, A Papageorgiou, N Papaoikonomou, S Antoniades, C Stefanadis, C The impact of diabetes mellitus on coronary artery disease: new therapeutic approaches. |
| title | The impact of diabetes mellitus on coronary artery disease: new therapeutic approaches. |
| title_full | The impact of diabetes mellitus on coronary artery disease: new therapeutic approaches. |
| title_fullStr | The impact of diabetes mellitus on coronary artery disease: new therapeutic approaches. |
| title_full_unstemmed | The impact of diabetes mellitus on coronary artery disease: new therapeutic approaches. |
| title_short | The impact of diabetes mellitus on coronary artery disease: new therapeutic approaches. |
| title_sort | impact of diabetes mellitus on coronary artery disease new therapeutic approaches |
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