HLA-A*68: 02-restricted Gag-specific cytotoxic T lymphocyte responses can drive selection pressure on HIV but are subdominant and ineffective

HLA-A*68: 02-restricted Gag-specific cytotoxic T lymphocyte responses can drive selection pressure on HIV but are subdominant and ineffective

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Background: Human leukocyte allele (HLA) class I polymorphism has the greatest impact of human genetic variation on viral load set point. A substantial part of this effect is due to the action of HLA-B and HLA-C alleles. With few exceptions the role of HLA-A molecules in immune control of HIV is unc...

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Bibliographic Details
Main Authors:	Kløverpris, H, Stryhn, A, Harndahl, M, Carlson, J, Leslie, A, Chen, F, Riddell, L, Mulenga, J, Walker, B, Ndung'U, T, Buus, S, Goulder, P
Format:	Journal article
Language:	English
Published:	2013

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