Effect of a 2-week interruption in methotrexate treatment versus continued treatment on COVID-19 booster vaccine immunity in adults with inflammatory conditions (VROOM study): a randomised, open label, superiority trial
<p><strong>Background</strong></p> Immunosuppressive treatments inhibit vaccine-induced immunity against SARS-CoV-2. We evaluated whether a 2-week interruption of methotrexate treatment immediately after the COVID-19 vaccine booster improved antibody responses against the S1...
Main Authors: | Abhishek, A, Boyton, RJ, Peckham, N, McKnight, Á, Coates, LC, Bluett, J, Barber, V, Cureton, L, Francis, A, Appelbe, D, Eldridge, L, Julier, P, Valdes, AM, Brooks, T, Rombach, I, Altmann, DM, Nguyen-Van-Tam, JS, Williams, HC, Cook, JA |
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其他作者: | VROOM study investigators |
格式: | Journal article |
语言: | English |
出版: |
Elsevier
2022
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