GATA1s induces hyperproliferation of eosinophil precursors in Down syndrome transient leukemia.

Transient leukemia (TL) is evident in 5-10% of all neonates with Down syndrome (DS) and associated with N-terminal truncating GATA1 mutations (GATA1s). Here we report that TL-cell clones generate abundant eosinophils in a substantial fraction of patients. Sorted eosinophils from patients with TL and...

Täydet tiedot

Bibliografiset tiedot
Päätekijät:	Maroz, A, Stachorski, L, Emmrich, S, Reinhardt, K, Xu, J, Shao, Z, Käbler, S, Dertmann, T, Hitzler, J, Roberts, I, Vyas, P, Juban, G, Hennig, C, Hansen, G, Li, Z, Orkin, S, Reinhardt, D, Klusmann, J
Aineistotyyppi:	Journal article
Kieli:	English
Julkaistu:	2014

GATA1s induces hyperproliferation of eosinophil precursors in Down syndrome transient leukemia Tekijä Maroz, A, Stachorski, L, Emmrich, S, Reinhardt, K, Xu, J, Shao, Z, Käbler, S, Dertmann, T, Hitzler, J, Roberts, I, Vyas, P, Juban, G, Hennig, C, Hansen, G, Li, Z, Orkin, S, Reinhardt, D, Klusmann, J

Julkaistu 2014

Journal article

GATA1s induces hyperproliferation of eosinophil precursors in Down syndrome transient leukemia.

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