Sendai virus-mediated CFTR gene transfer to the airway epithelium.

The potential for gene therapy to be an effective treatment for cystic fibrosis has been hampered by the limited gene transfer efficiency of current vectors. We have shown that recombinant Sendai virus (SeV) is highly efficient in mediating gene transfer to differentiated airway epithelial cells, be...

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Detalhes bibliográficos
Main Authors: Ferrari, S, Griesenbach, U, Iida, A, Farley, R, Wright, A, Zhu, J, Munkonge, F, Smith, SN, You, J, Ban, H, Inoue, M, Chan, M, Singh, C, Verdon, B, Argent, B, Wainwright, B, Jeffery, P, Geddes, D, Porteous, D, Hyde, S, Gray, M, Hasegawa, M, Alton, E
Formato: Journal article
Idioma:English
Publicado em: 2007