Carrier induced epitopic suppression of antibody responses induced by virus-like particles is a dynamic phenomenon caused by carrier-specific antibodies.

Pre-existing immunity against vaccine carrier proteins has been reported to inhibit the immune response against antigens conjugated to the same carrier by a process termed carrier induced epitopic suppression (CIES). Hence understanding the phenomenon of CIES is of major importance for the developme...

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Bibliographic Details
Main Authors: Jegerlehner, A, Wiesel, M, Dietmeier, K, Zabel, F, Gatto, D, Saudan, P, Bachmann, M
Format: Journal article
Language:English
Published: 2010

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