Carrier induced epitopic suppression of antibody responses induced by virus-like particles is a dynamic phenomenon caused by carrier-specific antibodies.
Pre-existing immunity against vaccine carrier proteins has been reported to inhibit the immune response against antigens conjugated to the same carrier by a process termed carrier induced epitopic suppression (CIES). Hence understanding the phenomenon of CIES is of major importance for the developme...
Main Authors: | Jegerlehner, A, Wiesel, M, Dietmeier, K, Zabel, F, Gatto, D, Saudan, P, Bachmann, M |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2010
|
Similar Items
-
Virus-like particles as carriers for T-cell epitopes: limited inhibition of T-cell priming by carrier-specific antibodies.
by: Ruedl, C, et al.
Published: (2005) -
Versatile virus-like particle carrier for epitope based vaccines
by: Tissot, A, et al.
Published: (2010) -
Bacterially produced recombinant influenza vaccines based on virus-like particles
by: Jegerlehner, A, et al.
Published: (2013) -
Low-affinity B cells transport viral particles from the lung to the spleen to initiate antibody responses.
by: Bessa, J, et al.
Published: (2012) -
Epitope resurfacing on dengue virus-like particle vaccine preparation to induce broad neutralizing antibody
by: Wen-Fan Shen, et al.
Published: (2018-10-01)