The H3 loop of antibodies shows unique structural characteristics
The H3 loop in the Complementary Determining Region (CDR) of antibodies plays a key role in their ability to bind the diverse space of potential antigens. It is also exceptionally difficult to model computationally causing a significant hurdle for in-silico development of antibody biotherapeutics....
Main Authors: | Regep, C, Georges, G, Shi, J, Popovic, B, Deane, C |
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Format: | Journal article |
Published: |
Wiley
2017
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