Pneumococcal genome sequencing tracks a vaccine escape variant formed through a multi-fragment recombination event.
Streptococcus pneumoniae ('pneumococcus') causes an estimated 14.5 million cases of serious disease and 826,000 deaths annually in children under 5 years of age(1). The highly effective introduction of the PCV7 pneumococcal vaccine in 2000 in the United States(2,3) provided an unprecedente...
Main Authors: | Golubchik, T, Brueggemann, A, Street, T, Gertz, R, Spencer, C, Ho, T, Giannoulatou, E, Link-Gelles, R, Harding, R, Beall, B, Peto, T, Moore, MR, Donnelly, P, Crook, D, Bowden, R |
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Format: | Journal article |
Language: | English |
Published: |
2012
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