Terminal exon definition occurs cotranscriptionally and promotes termination of RNA polymerase II.

Terminal exon definition occurs cotranscriptionally and promotes termination of RNA polymerase II.

Analysis of nascent transcription from the human epsilon- and beta-globin genes shows that transcriptional termination occurs within 1.5 kb of the poly(A) site and is dependent on the presence of functional poly(A) signals. Even so, transcripts that have not been cleaved at the poly(A) site are dete...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän:	Dye, M, Proudfoot, N
Materialtyp:	Journal article
Språk:	English
Publicerad:	1999

Liknande verk

Definition of RNA polymerase II CoTC terminator elements in the human genome.
av: Nojima, T, et al.
Publicerad: (2013)

Multiple transcript cleavage precedes polymerase release in termination by RNA polymerase II.
av: Dye, M, et al.
Publicerad: (2001)

Molecular dissection of mammalian RNA polymerase II transcriptional termination.
av: West, S, et al.
Publicerad: (2008)

Definition of RNA Polymerase II CoTC Terminator Elements in the Human Genome
av: Takayuki Nojima, et al.
Publicerad: (2013-04-01)

Exon tethering in transcription by RNA polymerase II.
av: Dye, M, et al.
Publicerad: (2006)

AT-rich sequence elements promote nascent transcript cleavage leading to RNA polymerase II termination.
av: White, E, et al.
Publicerad: (2013)

Pause sites promote transcriptional termination of mammalian RNA polymerase II.
av: Gromak, N, et al.
Publicerad: (2006)

Disengaging polymerase: terminating RNA polymerase II transcription in budding yeast.
av: Mischo, H, et al.
Publicerad: (2013)

Transcriptional termination in mammals: Stopping the RNA polymerase II juggernaut.
av: Proudfoot, N
Publicerad: (2016)

How RNA polymerase II terminates transcription in higher eukaryotes.
av: Proudfoot, N
Publicerad: (1989)

Transcriptional termination signals for RNA polymerase II in fission yeast.
av: Birse, C, et al.
Publicerad: (1997)

A pause site for RNA polymerase II is associated with termination of transcription.
av: Enriquez-Harris, P, et al.
Publicerad: (1991)

Modulating alternative splicing by cotranscriptional cleavage of nascent intronic RNA.
av: Gromak, N, et al.
Publicerad: (2008)

Transcription termination by RNA Polymerase II
av: White, E
Publicerad: (2012)

A role for chromatin remodeling in transcriptional termination by RNA polymerase II.
av: Alén, C, et al.
Publicerad: (2002)

Human Pcf11 enhances degradation of RNA polymerase II-associated nascent RNA and transcriptional termination.
av: West, S, et al.
Publicerad: (2008)

Human Pcf11 enhances degradation of RNA polymerase II-associated nascent RNA and transcriptional termination
av: West, S, et al.
Publicerad: (2008)

Coupling of PARP1-mediated chromatin structural changes to transcriptional RNA polymerase II elongation and cotranscriptional splicing
av: Elena A. Matveeva, et al.
Publicerad: (2019-02-01)

The conserved RNA-binding protein Seb1 promotes cotranscriptional ribosomal RNA processing by controlling RNA polymerase I progression
av: Maxime Duval, et al.
Publicerad: (2023-05-01)

Budding yeast RNA polymerases I and II employ parallel mechanisms of transcriptional termination.
av: Kawauchi, J, et al.
Publicerad: (2008)

Adenylation and exosome-mediated degradation of cotranscriptionally cleaved pre-messenger RNA in human cells.
av: West, S, et al.
Publicerad: (2006)

Cleavage/polyadenylation factor IA associates with the carboxyl-terminal domain of RNA polymerase II in Saccharomyces cerevisiae.
av: Barillà, D, et al.
Publicerad: (2001)

Isw1 chromatin remodeling ATPase coordinates transcription elongation and termination by RNA polymerase II.
av: Morillon, A, et al.
Publicerad: (2003)

Genome-wide mapping of yeast RNA polymerase II termination.
av: Paul Schaughency, et al.
Publicerad: (2014-10-01)

Role of the RNA/DNA kinase Grc3 in transcription termination by RNA polymerase I.
av: Braglia, P, et al.
Publicerad: (2010)

EM visualization of transcription by RNA polymerase II: downstream termination requires a poly(A) signal but not transcript cleavage.
av: Osheim, Y, et al.
Publicerad: (1999)

Co-transcriptional RNA cleavage provides a failsafe termination mechanism for yeast RNA polymerase I.
av: Braglia, P, et al.
Publicerad: (2011)

N-terminal tagging of RNA Polymerase II shapes transcriptomes more than C-terminal alterations
av: Adam Callan-Sidat, et al.
Publicerad: (2024-06-01)

Direct demonstration of termination signals for RNA polymerase II from the sea urchin H2A histone gene.
av: Briggs, D, et al.
Publicerad: (1989)

Turnover and function of noncoding RNA polymerase II transcripts.
av: Dye, M, et al.
Publicerad: (2006)

Decoding the informational properties of the RNA polymerase II Carboxy Terminal Domain
av: Karagiannis Jim
Publicerad: (2012-05-01)

Transcription termination and RNA degradation contribute to silencing of RNA polymerase II transcription within heterochromatin.
av: Vasiljeva, L, et al.
Publicerad: (2008)

Structural heterogeneity in the intrinsically disordered RNA polymerase II C-terminal domain
av: Bede Portz, et al.
Publicerad: (2017-05-01)

Autocatalytic RNA cleavage in the human beta-globin pre-mRNA promotes transcription termination.
av: Teixeira, A, et al.
Publicerad: (2004)

Role of R-loops in pause-dependent transcriptional termination of RNA polymerase II
av: Skourti-Stathaki, K
Publicerad: (2012)

Transcriptional termination by RNA polymerase I requires the small subunit Rpa12p.
av: Prescott, E, et al.
Publicerad: (2004)

Observation of coordinated RNA folding events by systematic cotranscriptional RNA structure probing
av: Courtney E. Szyjka, et al.
Publicerad: (2023-11-01)

Repeat-Specific Functions for the C-Terminal Domain of RNA Polymerase II in Budding Yeast
av: Michael Babokhov, et al.
Publicerad: (2018-05-01)

Role of the C-terminal domain of RNA polymerase II in expression of small nuclear RNA genes.
av: Egloff, S, et al.
Publicerad: (2008)

Driving forces behind phase separation of the carboxy-terminal domain of RNA polymerase II
av: David Flores-Solis, et al.
Publicerad: (2023-09-01)