Standing task difficulty related increase in agonist-agonist and agonist-antagonist common inputs are driven by corticospinal and subcortical inputs respectively
In standing, coordinated activation of lower extremity muscles can be simplified by common neural inputs to muscles comprising a functional synergy. We examined the effect of task difficulty on common inputs to agonist-agonist (AG-AG) pairs supporting direction specific reciprocal muscle control and...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Nature Research
2019
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| _version_ | 1826289419227758592 |
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| author | Nandi, T Hortobágyi, T van Keeken, H Salem, G Lamoth, C |
| author_facet | Nandi, T Hortobágyi, T van Keeken, H Salem, G Lamoth, C |
| author_sort | Nandi, T |
| collection | OXFORD |
| description | In standing, coordinated activation of lower extremity muscles can be simplified by common neural inputs to muscles comprising a functional synergy. We examined the effect of task difficulty on common inputs to agonist-agonist (AG-AG) pairs supporting direction specific reciprocal muscle control and agonist-antagonist (AG-ANT) pairs supporting stiffness control. Since excessive stiffness is energetically costly and limits the flexibility of responses to perturbations, compared to AG-ANT, we expected greater AG-AG common inputs and a larger increase with increasing task difficulty. We used coherence analysis to examine common inputs in three frequency ranges which reflect subcortical/spinal (0-5 and 6-15 Hz) and corticospinal inputs (6-15 and 16-40 Hz). Coherence was indeed higher in AG-AG compared to AG-ANT muscles in all three frequency bands, indicating a predilection for functional synergies supporting reciprocal rather than stiffness control. Coherence increased with increasing task difficulty, only in AG-ANT muscles in the low frequency band (0-5 Hz), reflecting subcortical inputs and only in AG-AG group in the high frequency band (16-40 Hz), reflecting corticospinal inputs. Therefore, common neural inputs to both AG-AG and AG-ANT muscles increase with difficulty but are likely driven by different sources of input to spinal alpha motor neurons. |
| first_indexed | 2024-03-07T02:28:35Z |
| format | Journal article |
| id | oxford-uuid:a67421b8-9acf-474b-9d22-ceeae50ee51d |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:28:35Z |
| publishDate | 2019 |
| publisher | Nature Research |
| record_format | dspace |
| spelling | oxford-uuid:a67421b8-9acf-474b-9d22-ceeae50ee51d2022-03-27T02:47:34ZStanding task difficulty related increase in agonist-agonist and agonist-antagonist common inputs are driven by corticospinal and subcortical inputs respectivelyJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a67421b8-9acf-474b-9d22-ceeae50ee51dEnglishSymplectic Elements at OxfordNature Research2019Nandi, THortobágyi, Tvan Keeken, HSalem, GLamoth, CIn standing, coordinated activation of lower extremity muscles can be simplified by common neural inputs to muscles comprising a functional synergy. We examined the effect of task difficulty on common inputs to agonist-agonist (AG-AG) pairs supporting direction specific reciprocal muscle control and agonist-antagonist (AG-ANT) pairs supporting stiffness control. Since excessive stiffness is energetically costly and limits the flexibility of responses to perturbations, compared to AG-ANT, we expected greater AG-AG common inputs and a larger increase with increasing task difficulty. We used coherence analysis to examine common inputs in three frequency ranges which reflect subcortical/spinal (0-5 and 6-15 Hz) and corticospinal inputs (6-15 and 16-40 Hz). Coherence was indeed higher in AG-AG compared to AG-ANT muscles in all three frequency bands, indicating a predilection for functional synergies supporting reciprocal rather than stiffness control. Coherence increased with increasing task difficulty, only in AG-ANT muscles in the low frequency band (0-5 Hz), reflecting subcortical inputs and only in AG-AG group in the high frequency band (16-40 Hz), reflecting corticospinal inputs. Therefore, common neural inputs to both AG-AG and AG-ANT muscles increase with difficulty but are likely driven by different sources of input to spinal alpha motor neurons. |
| spellingShingle | Nandi, T Hortobágyi, T van Keeken, H Salem, G Lamoth, C Standing task difficulty related increase in agonist-agonist and agonist-antagonist common inputs are driven by corticospinal and subcortical inputs respectively |
| title | Standing task difficulty related increase in agonist-agonist and agonist-antagonist common inputs are driven by corticospinal and subcortical inputs respectively |
| title_full | Standing task difficulty related increase in agonist-agonist and agonist-antagonist common inputs are driven by corticospinal and subcortical inputs respectively |
| title_fullStr | Standing task difficulty related increase in agonist-agonist and agonist-antagonist common inputs are driven by corticospinal and subcortical inputs respectively |
| title_full_unstemmed | Standing task difficulty related increase in agonist-agonist and agonist-antagonist common inputs are driven by corticospinal and subcortical inputs respectively |
| title_short | Standing task difficulty related increase in agonist-agonist and agonist-antagonist common inputs are driven by corticospinal and subcortical inputs respectively |
| title_sort | standing task difficulty related increase in agonist agonist and agonist antagonist common inputs are driven by corticospinal and subcortical inputs respectively |
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