Interactions between PPAR-α and inflammation-related cytokine genes on the development of Alzheimer's disease, observed by the Epistasis project

Neuroinflammation contributes to the pathogenesis of sporadic Alzheimer's disease (AD). Variations in genes relevant to inflammation may be candidate genes for AD risk. Whole-genome association studies have identified relevant new and known genes. Their combined effects do not explain 100% of t...

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Autors principals: Heun, R, Kölsch, H, Ibrahim-Verbaas, C, Combarros, O, Aulchenko, Y, Breteler, M, Schuur, M, van Duijn, C, Hammond, N, Belbin, O, Cortina-Borja, M, Wilcock, G, Brown, K, Barber, R, Kehoe, P, Coto, E, Alvarez, V, Lehmann, MG, Deloukas, P, Mateo, I, Morgan, K, Warden, DR
Format: Journal article
Publicat: 2012