Suppression of thromboxane A2 but not of systemic prostacyclin by controlled-release aspirin.

Suppression of thromboxane A2 but not of systemic prostacyclin by controlled-release aspirin.

BACKGROUND: The antithrombotic efficacy of aspirin is attributed to its inhibition of the enzyme prostaglandin G/H synthase, which is necessary for the formation of thromboxane A2 in platelets. Thromboxane A2 is a potent vasoconstrictor and platelet agonist. However, the formation of prostacyclin by...

书目详细资料
Main Authors:	Clarke, R, Mayo, G, Price, P, FitzGerald, G
格式:	Journal article
语言:	English
出版:	1991

相似书籍

Combined administration of aspirin and a specific thrombin inhibitor in man.
由: Clarke, R, et al.
出版: (1991)

Aspirin affects early phases of metastasis through the inhibition of COX-1-thromboxane A2 axis
由: Lucotti, S
出版: (2016)

Aspirin blocks formation of metastatic intravascular niches by inhibiting platelet-derived COX-1/thromboxane A2
由: Lucotti, S, et al.
出版: (2019)

Divergent roles of prostacyclin and PGE2 in human tendinopathy.
由: Bergqvist, F, et al.
出版: (2019)

Effect of low-dose aspirin on urinary 11-dehydro-thromboxane B2 in the ASCEND (A Study of Cardiovascular Events iN Diabetes) randomized controlled trial
由: Parish, S, et al.
出版: (2023)

Suppression of scarring in peripheral nerve implants by drug elution
由: FitzGerald, J
出版: (2016)

Quantitative studies on the effect of prostacyclin on freshly isolated rat osteoclasts in culture.
由: Adebanjo, O, et al.
出版: (1994)

Thromboxane biosynthesis and future events in diabetes: the ASCEND trial
由: Petrucci, G, et al.
出版: (2024)

Prostacyclin: a potential novel therapeutic target to treat tendon pain and inflammation
由: Bergqvist, F, et al.
出版: (2018)

Insect suppression with controlled release pheromone systems /
由: Kydonieus, Agis F., et al.
出版: (1982)

Nitric oxide-releasing aspirin: will it say NO to atherothrombosis?
由: Antoniades, C, et al.
出版: (2007)

Understanding development of vasculopathy in diabetic microcirculation - role of endothelial prostanoids, prostacyclin and nitric oxide
由: Rasool, Aida Hanum Ghulam
出版: (2019)

Cyclooxygenase-2 derived thromboxane A(2) and reactive oxygen species mediate flow-induced constrictions of venules in hyperhomocysteinemia.
由: Racz, A, et al.
出版: (2010)

Once daily low-dose aspirin reduces urinary thromboxane B2 effectively even at 12-24 hours from dosing in the ASCEND (A Study of Cardiovascular Events iN Diabetes) trial
由: Aung, T, et al.
出版: (2017)

Thromboxane A2 inhibition of SKCa after NO synthase block in rat middle cerebral artery.
由: McNeish, A, et al.
出版: (2007)

Prediction of favourable responses to long term vasodilator treatment of pulmonary hypertension by short term administration of epoprostenol (prostacyclin) or nifedipine.
由: Rozkovec, A, et al.
出版: (1988)

The Economics of Airport Development and Control.
由: FitzGerald, E, et al.
出版: (1973)

Policy Issues in Market-Based and Non-market-Based Measures to Control the Volatility of Portfolio Investment.
由: FitzGerald, E
出版: (2005)

Modelos monetarios y control de la inflacion en las economias de mercado emergentes. (With English summary.)
由: FitzGerald, V
出版: (2005)

Thromboxane A(2) contributes to the mediation of flow-induced responses of skeletal muscle venules: role of cyclooxygenases 1 and 2.
由: Racz, A, et al.
出版: (2009)

Aspirin, salicylates and cancer
由: Morgan, G, et al.
出版: (2011)

INHIBITION OF THROMBOXANE SYNTHESIS AND OF ARACHIDONATE-INDUCED PLATELET BEHAVIOR IN PLATELETS FROM DIFFERENT INDIVIDUALS
由: Heptinstall, S, et al.
出版: (1981)

Glucagon-like peptide-1 receptor regulates thromboxane-induced human platelet activation
由: Cahill, KN, et al.
出版: (2022)

Aspirin and stroke.
由: Buring, J, et al.
出版: (1990)

Thromboxane receptor stimulation associated with loss of SKCa activity and reduced EDHF responses in the rat isolated mesenteric artery.
由: Crane, G, et al.
出版: (2004)

Thromboxane metabolite excretion is associated with serious vascular events in diabetes mellitus: a sub-study of the ASCEND trial
由: Rocca, B, et al.
出版: (2020)

Flow-induced constriction in arterioles of hyperhomocysteinemic rats is due to impaired nitric oxide and enhanced thromboxane A(2) mediation.
由: Bagi, Z, et al.
出版: (2001)

Aspirin and the stomach.
由: Langston, H
出版: (1981)

Use of Geographic Information Systems (GIS) to aid in siting dredged material disposal areas
由: FitzGerald, Scott T., 1974-
出版: (2009)

The Regional Monetary System and Economic Recovery.
由: FitzGerald, E, et al.
出版: (1989)

Aspirin for everyone older than 50? For.
由: Elwood, P, et al.
出版: (2005)

ENDOGENOUS OPIOID SUPPRESSION OF CATECHOLAMINE RELEASE IS NOT MEDIATED BY CIRCULATING MET-ENKEPHALIN
由: Grossman, A, et al.
出版: (1986)

Nicaragua: Economic Crisis and Transition on the Periphery.
由: FitzGerald, E
出版: (1991)

ECLA and the formation of Latin American economic doctrine in the nineteenforties.
由: FitzGerald, E
出版: (1991)

Economic reform and citizen entitlements in Eastern Europe: some social implications of structural adjustment in semi-industrial economies.
由: FitzGerald, E
出版: (1991)

Introduction: The Central American Agro-export Economy--Issues and Debates.
由: FitzGerald, E
出版: (1991)

International Tax Co-operation and Capital Mobility.
由: FitzGerald, V
出版: (2002)

ECLA and the Formation of Latin American Economic Doctrine.
由: FitzGerald, E
出版: (1994)

State Accumulation and Market Equilibria: An Application of Kalecki-Kornai Analysis to Planned Economies in the Third World.
由: FitzGerald, E
出版: (1988)

Getting past 'purposeful': Exploring dimensionality in nonprofit executive performance information use
由: FitzGerald, C
出版: (2020)