Suppression of thromboxane A2 but not of systemic prostacyclin by controlled-release aspirin.

Suppression of thromboxane A2 but not of systemic prostacyclin by controlled-release aspirin.

BACKGROUND: The antithrombotic efficacy of aspirin is attributed to its inhibition of the enzyme prostaglandin G/H synthase, which is necessary for the formation of thromboxane A2 in platelets. Thromboxane A2 is a potent vasoconstrictor and platelet agonist. However, the formation of prostacyclin by...

書誌詳細
主要な著者:	Clarke, R, Mayo, G, Price, P, FitzGerald, G
フォーマット:	Journal article
言語:	English
出版事項:	1991

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