Electrohydrodynamic comminution: a novel technique for the aerosolisation of plasmid DNA.

PURPOSE: Naked plasmid DNA (pDNA) is a potential gene transfer agent for lung gene therapies but cannot be aerosolised without degradation using conventional nebulisation devices. This study investigated the viability of an alternative nebulisation technique, electrohydrodynamic (EHD) comminution f...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Davies, L, Hannavy, K, Davies, N, Pirrie, A, Coffee, R, Hyde, S, Gill, DR
Format: Journal article
Sprache:English
Veröffentlicht: 2005