Proline-induced distortions of transmembrane helices.

Proline residues in the transmembrane (TM) alpha-helices of integral membrane proteins have long been suspected to play a key role for helix packing and signal transduction by inducing regions of helix distortion and/or dynamic flexibility (hinges). In this study we try to characterise the effect of...

Full description

Bibliographic Details
Main Authors: Cordes, F, Bright, J, Sansom, MS
Format: Journal article
Language:English
Published: 2002