CTGF IS RELEASED FROM THE PERICELLULAR MATRIX OF ARTICULAR CARTILAGE UPON MECHANICAL INJURY, AND CONTROLS THE BIOAVAILABILITY OF TGF beta

CTGF IS RELEASED FROM THE PERICELLULAR MATRIX OF ARTICULAR CARTILAGE UPON MECHANICAL INJURY, AND CONTROLS THE BIOAVAILABILITY OF TGF beta

Bibliografiske detaljer
Main Authors:	Tang, X, McLean, C, Chanalaris, A, Vincent, T
Format:	Journal article
Udgivet:	2014

Lignende værker

CTGF is released from the pericellular matrix of articular cartilage upon mechanical injury, and promotes the bioavailability of TGF beta
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Udgivet: (2014)

CTGF is a pericellular protein whose cellular response is dependent upon the TGF beta type I receptor
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Udgivet: (2013)

Pericellular matrix of articular cartilage. A novel mechanotransduction mechanism in articular chondrocytes?
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Udgivet: (2006)

Structural and regulatory components of the pericellular matrix of young and mature articular cartilage
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Udgivet: (2010)

FGF-2 is bound to perlecan in the pericellular matrix of articular cartilage, where it acts as a chondrocyte mechanotransducer.
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Udgivet: (2007)

Probing nanomechanics of aggrecan and the aggrecan-rich pericellular matrix of chondrocytes in cartilage
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Connective tissue growth factor: matrix localisation, regulation and possible function in articular cartilage
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Udgivet: (2010)

Cartilage-derived cells display heterogeneous pericellular matrix synthesis in agarose microgels
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Udgivet: (2024-08-01)

Connective Tissue Growth Factor (CTGF) contributes to joint homeostasis and osteoarthritis severity by controlling the matrix sequestration and activation of latent TGFβ
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Udgivet: (2018)

Direct Perfusion Improves Redifferentiation of Human Chondrocytes in Fibrin Hydrogel with the Deposition of Cartilage Pericellular Matrix
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Udgivet: (2021-09-01)

Matrix-bound growth factors are released upon cartilage compression by an aggrecan-dependent sodium flux that is lost in osteoarthritis
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Udgivet: (2021)

Targeting mechanotransduction pathways in osteoarthritis: a focus on the pericellular matrix.
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Udgivet: (2013)

Targeting mechanotransduction pathways in osteoarthritis: a focus on the pericellular matrix
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Udgivet: (2013)

Targeting mechanotransduction pathways in osteoarthritis: a focus on the pericellular matrix.
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Mechanical stress determines the configuration of TGFβ activation in articular cartilage
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Udgivet: (2021-03-01)

Extracellular Matrix (ECM) Multilayer Membrane as a Sustained Releasing Growth Factor Delivery System for rhTGF-β3 in Articular Cartilage Repair.
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Udgivet: (2016-01-01)

TGF-β1 Improves Articular Cartilage Damage in Rabbit Knee
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Cyclic mechanical load causes global translational arrest in articular chondrocytes: a process which is partially dependent upon PKR phosphorylation.
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Bioavailability of matrix-bound growth factors in cartilage injury
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Udgivet: (2021)

CTGF as a multifunctional molecule for cartilage and a potential drug for osteoarthritis
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Udgivet: (2022-10-01)

Runx1 is a key regulator of articular cartilage homeostasis by orchestrating YAP, TGFβ, and Wnt signaling in articular cartilage formation and osteoarthritis
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Udgivet: (2022-10-01)

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Udgivet: (2021-02-01)

The effects of hydrostatic pressure on matrix synthesis in articular cartilage.
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Udgivet: (1991)

The role of TGF-beta3 in cartilage development and osteoarthritis
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Udgivet: (2023-01-01)

Cartilage injury suppresses endogenous retinoic acid through activation of TGFβ-activated kinase 1 (TAK1)
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Udgivet: (2018)

Articular cartilage /
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Udgivet: (c201)

ARTICULAR CARTILAGE /
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Udgivet: (2017)

Bi-directional cell-pericellular matrix interactions direct stem cell fate
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Udgivet: (2018-10-01)

WARP interacts with collagen VI-containing microfibrils in the pericellular matrix of human chondrocytes.
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Bovine articular cartilage decellularized matrix as a scaffold for use in cartilage tissue engineering
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Inhibition of RhoA/Rho-kinase pathway suppresses the expression of extracellular matrix induced by CTGF or TGF- β in ARPE-19
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Udgivet: (2013-02-01)

Adult articular cartilage culture system and effects of IL-1[beta]
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Udgivet: (2008)

Cartilage damage involving extrusion of mineralisable matrix from the articular calcified cartilage and subchondral bone
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Udgivet: (2011-05-01)