Inferring strain mixture within clinical plasmodium falciparum isolates from genomic sequence data
We present a rigorous statistical model that infers the structure of P. falciparum mixtures-including the number of strains present, their proportion within the samples, and the amount of unexplained mixture-using whole genome sequence (WGS) data. Applied to simulation data, artificial laboratory mi...
Main Authors: | O'Brien, J, Iqbal, Z, Wendler, J, Amenga-Etego, L |
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Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2016
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