Inferring strain mixture within clinical plasmodium falciparum isolates from genomic sequence data

We present a rigorous statistical model that infers the structure of P. falciparum mixtures-including the number of strains present, their proportion within the samples, and the amount of unexplained mixture-using whole genome sequence (WGS) data. Applied to simulation data, artificial laboratory mi...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính: O'Brien, J, Iqbal, Z, Wendler, J, Amenga-Etego, L
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Public Library of Science 2016