Clinical characteristics of subjects with a missense mutation in glucokinase.

Clinical characteristics of subjects with a missense mutation in glucokinase.

The clinical characteristics of subjects with a missense glucokinase mutation, gly299-->arg, were studied in a large pedigree, BX, initially characterized by some members having Maturity Onset Diabetes of the Young (MODY). Glucose tolerance, beta cell function and insulin sensitivity were mea...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Page, R, Hattersley, A, Levy, J, Barrow, B, Patel, P, Lo, D, Wainscoat, J, Permutt, M, Bell, G, Turner, R
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	1995

Eitemau Tebyg

High prevalence of a missense mutation of the glucokinase gene in gestational diabetic patients due to a founder-effect in a local population.
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