Coming together to define membrane contact sites
Close proximities between organelles have been described for decades. However, only recently a specific field dealing with organelle communication at membrane contact sites has gained wide acceptance, attracting scientists from multiple areas of cell biology. The diversity of approaches warrants a u...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Springer Nature
2019
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| _version_ | 1797087025986273280 |
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| author | Scorrano, L Matteis, D Emr, S Giordano, F Hajnóczky, G Kornmann, B Lackner, L Levine, T Pellegrini, L Reinisch, K Rizzuto, R Simmen, T Stenmark, H Ungermann, C Schuldiner, M |
| author_facet | Scorrano, L Matteis, D Emr, S Giordano, F Hajnóczky, G Kornmann, B Lackner, L Levine, T Pellegrini, L Reinisch, K Rizzuto, R Simmen, T Stenmark, H Ungermann, C Schuldiner, M |
| author_sort | Scorrano, L |
| collection | OXFORD |
| description | Close proximities between organelles have been described for decades. However, only recently a specific field dealing with organelle communication at membrane contact sites has gained wide acceptance, attracting scientists from multiple areas of cell biology. The diversity of approaches warrants a unified vocabulary for the field. Such definitions would facilitate laying the foundations of this field, streamlining communication and resolving semantic controversies. This opinion, written by a panel of experts in the field, aims to provide this burgeoning area with guidelines for the experimental definition and analysis of contact sites. It also includes suggestions on how to operationally and tractably measure and analyze them with the hope of ultimately facilitating knowledge production and dissemination within and outside the field of contact-site research. |
| first_indexed | 2024-03-07T02:30:17Z |
| format | Journal article |
| id | oxford-uuid:a6ffded1-198f-423d-b7b2-204a7d7c4d95 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:30:17Z |
| publishDate | 2019 |
| publisher | Springer Nature |
| record_format | dspace |
| spelling | oxford-uuid:a6ffded1-198f-423d-b7b2-204a7d7c4d952022-03-27T02:51:30ZComing together to define membrane contact sitesJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a6ffded1-198f-423d-b7b2-204a7d7c4d95EnglishSymplectic Elements at OxfordSpringer Nature2019Scorrano, LMatteis, DEmr, SGiordano, FHajnóczky, GKornmann, BLackner, LLevine, TPellegrini, LReinisch, KRizzuto, RSimmen, TStenmark, HUngermann, CSchuldiner, MClose proximities between organelles have been described for decades. However, only recently a specific field dealing with organelle communication at membrane contact sites has gained wide acceptance, attracting scientists from multiple areas of cell biology. The diversity of approaches warrants a unified vocabulary for the field. Such definitions would facilitate laying the foundations of this field, streamlining communication and resolving semantic controversies. This opinion, written by a panel of experts in the field, aims to provide this burgeoning area with guidelines for the experimental definition and analysis of contact sites. It also includes suggestions on how to operationally and tractably measure and analyze them with the hope of ultimately facilitating knowledge production and dissemination within and outside the field of contact-site research. |
| spellingShingle | Scorrano, L Matteis, D Emr, S Giordano, F Hajnóczky, G Kornmann, B Lackner, L Levine, T Pellegrini, L Reinisch, K Rizzuto, R Simmen, T Stenmark, H Ungermann, C Schuldiner, M Coming together to define membrane contact sites |
| title | Coming together to define membrane contact sites |
| title_full | Coming together to define membrane contact sites |
| title_fullStr | Coming together to define membrane contact sites |
| title_full_unstemmed | Coming together to define membrane contact sites |
| title_short | Coming together to define membrane contact sites |
| title_sort | coming together to define membrane contact sites |
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