The mannose receptor binds Trichuris muris excretory/secretory proteins but is not essential for protective immunity.

Trichuris muris is a natural mouse model of the human gastrointestinal nematode parasite Trichuris trichiura and it is well established that a T helper type 2-dominated immune response is required for worm expulsion. Macrophages accumulate in the large intestine of mice during infection and these ce...

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Bibliographic Details
Main Authors: deSchoolmeester, M, Martinez-Pomares, L, Gordon, S, Else, K
Format: Journal article
Language:English
Published: 2009

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