MHC class II expression in double mutant mice lacking invariant chain and DM functions.
Invariant (Ii) chain and DM functions are required at distinct stages during class II maturation to promote occupancy by diverse peptide ligands. The class II molecules expressed by mutant mouse strains lacking Ii chain or DM activities display discrete structural and functional abnormalities. The p...
Main Authors: | Kenty, G, Martin, W, Van Kaer, L, Bikoff, E |
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Format: | Journal article |
Language: | English |
Published: |
1998
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