SnoopLigase catalyzes peptide-peptide locking and enables solid-phase conjugate isolation

<p>Simple, efficient reactions for connecting biological building-blocks open up many new possibilities. Here we have designed SnoopLigase, a protein that catalyzes site-specific transamidation, forming an isopeptide bond with more than 95% efficiency between two peptide tags, SnoopTagJr and...

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Bibliographic Details
Main Authors: Buldun, C, Jean, J, Bedford, M, Howarth, M
Format: Journal article
Published: American Chemical Society 2018