Prion-like spreading of Alzheimer's disease within the brain's connectome
The prion hypothesis states that misfolded proteins can act as infectious agents that template the misfolding and aggregation of healthy proteins to transmit a disease. Increasing evidence suggests that pathological proteins in neurodegenerative diseases adopt prion-like mechanisms and spread across...
Hauptverfasser: | Fornari, S, Schäfer, A, Jucker, M, Goriely, A, Kuhl, E |
---|---|
Format: | Journal article |
Veröffentlicht: |
Royal Society
2019
|
Ähnliche Einträge
Ähnliche Einträge
-
Spatially-extended nucleation-aggregation-fragmentation models for the dynamics of prion-like neurodegenerative protein-spreading in the brain and its connectome
von: Fornari, S, et al.
Veröffentlicht: (2019) -
A physics-based model explains the prion-like features of neurodegeneration in Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis
von: Weickenmeier, J, et al.
Veröffentlicht: (2018) -
The multiphysics of prion-like diseases: progression and atrophy
von: Weickenmeier, J, et al.
Veröffentlicht: (2018) -
Mapping the Alzheimer's brain with connectomics
von: Teng eXie, et al.
Veröffentlicht: (2012-01-01) -
Fingerprints of brain disease: connectome identifiability in Alzheimer’s disease
von: Sara Stampacchia, et al.
Veröffentlicht: (2024-09-01)