Prion-like spreading of Alzheimer's disease within the brain's connectome
The prion hypothesis states that misfolded proteins can act as infectious agents that template the misfolding and aggregation of healthy proteins to transmit a disease. Increasing evidence suggests that pathological proteins in neurodegenerative diseases adopt prion-like mechanisms and spread across...
Main Authors: | Fornari, S, Schäfer, A, Jucker, M, Goriely, A, Kuhl, E |
---|---|
格式: | Journal article |
出版: |
Royal Society
2019
|
相似书籍
-
Spatially-extended nucleation-aggregation-fragmentation models for the dynamics of prion-like neurodegenerative protein-spreading in the brain and its connectome
由: Fornari, S, et al.
出版: (2019) -
A physics-based model explains the prion-like features of neurodegeneration in Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis
由: Weickenmeier, J, et al.
出版: (2018) -
The multiphysics of prion-like diseases: progression and atrophy
由: Weickenmeier, J, et al.
出版: (2018) -
Fingerprints of brain disease: connectome identifiability in Alzheimer’s disease
由: Sara Stampacchia, et al.
出版: (2024-09-01) -
Prion-like Spreading of Disease in TDP-43 Proteinopathies
由: Emma Pongrácová, et al.
出版: (2024-11-01)