RPA activates the XPF‐ERCC1 endonuclease to initiate processing of DNA interstrand crosslinks

RPA activates the XPF‐ERCC1 endonuclease to initiate processing of DNA interstrand crosslinks

عرض إصدارات أخرى (1)

During replication‐coupled DNA interstrand crosslink (ICL) repair, the XPF‐ERCC1 endonuclease is required for the incisions that release, or “unhook”, ICLs, but the mechanism of ICL unhooking remains largely unknown. Incisions are triggered when the nascent leading strand of a replication fork strik...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Abdullah, U, McGouran, J, Brolih, S, Ptchelkine, D, El-Sagheer, A, Brown, T, McHugh, P
التنسيق:	Journal article
منشور في:	EMBO Press 2017

مواد مشابهة

RPA activates the XPF-ERCC1 endonuclease to initiate processing of DNA interstrand crosslinks.
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