Microbial genome sequencing and pathogenesis.

The year 1997 saw the publication of the complete nucleotide sequence of Helicobacter pylori and Escherichia coli. It is conceivable that the complete nucleotide sequence for all the major human bacterial pathogens will be available by the end of the century. Database alignments have been used to as...

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Main Authors: Tang, C, Hood, D, Moxon, E
Format: Journal article
Language:English
Published: 1998
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author Tang, C
Hood, D
Moxon, E
author_facet Tang, C
Hood, D
Moxon, E
author_sort Tang, C
collection OXFORD
description The year 1997 saw the publication of the complete nucleotide sequence of Helicobacter pylori and Escherichia coli. It is conceivable that the complete nucleotide sequence for all the major human bacterial pathogens will be available by the end of the century. Database alignments have been used to ascribe the putative functions of open reading frames in the sequenced isolates and to define the differences between bacterial species at the nucleotide level. The most striking finding from all genome projects has been the high proportion of open reading frames that have no known function. Experimental data demonstrating the utility of the genome sequencing projects are only just beginning to emerge.
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spelling oxford-uuid:a7662c3a-9f73-4ade-a383-8cb226ddfe352022-03-27T02:54:24ZMicrobial genome sequencing and pathogenesis.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a7662c3a-9f73-4ade-a383-8cb226ddfe35EnglishSymplectic Elements at Oxford1998Tang, CHood, DMoxon, EThe year 1997 saw the publication of the complete nucleotide sequence of Helicobacter pylori and Escherichia coli. It is conceivable that the complete nucleotide sequence for all the major human bacterial pathogens will be available by the end of the century. Database alignments have been used to ascribe the putative functions of open reading frames in the sequenced isolates and to define the differences between bacterial species at the nucleotide level. The most striking finding from all genome projects has been the high proportion of open reading frames that have no known function. Experimental data demonstrating the utility of the genome sequencing projects are only just beginning to emerge.
spellingShingle Tang, C
Hood, D
Moxon, E
Microbial genome sequencing and pathogenesis.
title Microbial genome sequencing and pathogenesis.
title_full Microbial genome sequencing and pathogenesis.
title_fullStr Microbial genome sequencing and pathogenesis.
title_full_unstemmed Microbial genome sequencing and pathogenesis.
title_short Microbial genome sequencing and pathogenesis.
title_sort microbial genome sequencing and pathogenesis
work_keys_str_mv AT tangc microbialgenomesequencingandpathogenesis
AT hoodd microbialgenomesequencingandpathogenesis
AT moxone microbialgenomesequencingandpathogenesis