Universal bispecific antibody for targeting tumor cells for destruction by cytotoxic T cells.
Previous studies have demonstrated that bispecific hybrid antibodies produced by cell-cell fusion or chemically conjugated heteroaggregates can direct cytotoxic T lymphocytes to kill target cells for which they have no intrinsic specificity, a phenomenon we call effector cell retargeting (ECR). Thes...
Prif Awduron: | Gilliland, L, Clark, MR, Waldmann, H |
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Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
1988
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Eitemau Tebyg
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T-cell killing of target cells induced by hybrid antibodies: comparison of two bispecific monoclonal antibodies.
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Development of humanized bispecific antibodies reactive with cytotoxic lymphocytes and tumor cells overexpressing the HER2 protooncogene.
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Cyhoeddwyd: (1992) -
Oncolytic adenovirus expressing bispecific antibody targets T‐cell cytotoxicity in cancer biopsies
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Cyhoeddwyd: (2017) -
Oncolytic adenovirus expressing bispecific antibody targets T‐cell cytotoxicity in cancer biopsies
gan: Joshua D Freedman, et al.
Cyhoeddwyd: (2017-06-01) -
Bispecific antibody-activated T cells enhance NK cell-mediated antibody-dependent cellular cytotoxicity
gan: Zhaoming Wang, et al.
Cyhoeddwyd: (2021-12-01)