Universal bispecific antibody for targeting tumor cells for destruction by cytotoxic T cells.
Previous studies have demonstrated that bispecific hybrid antibodies produced by cell-cell fusion or chemically conjugated heteroaggregates can direct cytotoxic T lymphocytes to kill target cells for which they have no intrinsic specificity, a phenomenon we call effector cell retargeting (ECR). Thes...
Автори: | Gilliland, L, Clark, MR, Waldmann, H |
---|---|
Формат: | Journal article |
Мова: | English |
Опубліковано: |
1988
|
Схожі ресурси
Схожі ресурси
-
T-cell killing of target cells induced by hybrid antibodies: comparison of two bispecific monoclonal antibodies.
за авторством: Clark, MR, та інші
Опубліковано: (1987) -
Development of humanized bispecific antibodies reactive with cytotoxic lymphocytes and tumor cells overexpressing the HER2 protooncogene.
за авторством: Shalaby, MR, та інші
Опубліковано: (1992) -
Oncolytic adenovirus expressing bispecific antibody targets T‐cell cytotoxicity in cancer biopsies
за авторством: Freedman, J, та інші
Опубліковано: (2017) -
Oncolytic adenovirus expressing bispecific antibody targets T‐cell cytotoxicity in cancer biopsies
за авторством: Joshua D Freedman, та інші
Опубліковано: (2017-06-01) -
Bispecific antibody-activated T cells enhance NK cell-mediated antibody-dependent cellular cytotoxicity
за авторством: Zhaoming Wang, та інші
Опубліковано: (2021-12-01)