Universal bispecific antibody for targeting tumor cells for destruction by cytotoxic T cells.
Previous studies have demonstrated that bispecific hybrid antibodies produced by cell-cell fusion or chemically conjugated heteroaggregates can direct cytotoxic T lymphocytes to kill target cells for which they have no intrinsic specificity, a phenomenon we call effector cell retargeting (ECR). Thes...
| Main Authors: | , , |
|---|---|
| Formato: | Journal article |
| Idioma: | English |
| Publicado em: |
1988
|