Universal bispecific antibody for targeting tumor cells for destruction by cytotoxic T cells.

Previous studies have demonstrated that bispecific hybrid antibodies produced by cell-cell fusion or chemically conjugated heteroaggregates can direct cytotoxic T lymphocytes to kill target cells for which they have no intrinsic specificity, a phenomenon we call effector cell retargeting (ECR). Thes...

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Chi tiết về thư mục
Những tác giả chính: Gilliland, L, Clark, MR, Waldmann, H
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 1988