Glycosylated siglec6 expression in syncytiotrophoblast-derived extracellular vesicles from preeclamptic placentas
Preeclampsia (PE) is associated with an exaggerated maternal systemic inflammatory response. The placenta releases extracellular vesicles from its syncytiotrophoblast layer (STBEV) into the maternal circulation. Expression of Siglec6, a transmembrane receptor of molecular weight 50kDa, is known to...
| Autori principali: | , , , , , , , , , , , |
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| Natura: | Conference item |
| Pubblicazione: |
Elsevier
2018
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| _version_ | 1826289627515846656 |
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| author | White, K Tannetta, D Kandzija, N Motta-Mejia, C Gill, M Zhang, W Cooke, W Thammasate, B Cerdeira, S Ri, R Redman, C Vatish, M |
| author_facet | White, K Tannetta, D Kandzija, N Motta-Mejia, C Gill, M Zhang, W Cooke, W Thammasate, B Cerdeira, S Ri, R Redman, C Vatish, M |
| author_sort | White, K |
| collection | OXFORD |
| description | Preeclampsia (PE) is associated with an exaggerated maternal systemic inflammatory response. The placenta releases extracellular vesicles from its syncytiotrophoblast layer (STBEV) into the maternal circulation. Expression of Siglec6, a transmembrane receptor of molecular weight 50kDa, is known to be upregulated in PE placental lysate (PL). Here we investigate the abundance of Siglec6 in STBEV, and whether the levels are different between PE and normal STBEV. |
| first_indexed | 2024-03-07T02:31:46Z |
| format | Conference item |
| id | oxford-uuid:a779a547-4b22-4c47-a5be-f587c3f2c36d |
| institution | University of Oxford |
| last_indexed | 2024-03-07T02:31:46Z |
| publishDate | 2018 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:a779a547-4b22-4c47-a5be-f587c3f2c36d2022-03-27T02:54:53ZGlycosylated siglec6 expression in syncytiotrophoblast-derived extracellular vesicles from preeclamptic placentasConference itemhttp://purl.org/coar/resource_type/c_5794uuid:a779a547-4b22-4c47-a5be-f587c3f2c36dSymplectic Elements at OxfordElsevier2018White, KTannetta, DKandzija, NMotta-Mejia, CGill, MZhang, WCooke, WThammasate, BCerdeira, SRi, RRedman, CVatish, M Preeclampsia (PE) is associated with an exaggerated maternal systemic inflammatory response. The placenta releases extracellular vesicles from its syncytiotrophoblast layer (STBEV) into the maternal circulation. Expression of Siglec6, a transmembrane receptor of molecular weight 50kDa, is known to be upregulated in PE placental lysate (PL). Here we investigate the abundance of Siglec6 in STBEV, and whether the levels are different between PE and normal STBEV. |
| spellingShingle | White, K Tannetta, D Kandzija, N Motta-Mejia, C Gill, M Zhang, W Cooke, W Thammasate, B Cerdeira, S Ri, R Redman, C Vatish, M Glycosylated siglec6 expression in syncytiotrophoblast-derived extracellular vesicles from preeclamptic placentas |
| title | Glycosylated siglec6 expression in syncytiotrophoblast-derived extracellular vesicles from preeclamptic placentas |
| title_full | Glycosylated siglec6 expression in syncytiotrophoblast-derived extracellular vesicles from preeclamptic placentas |
| title_fullStr | Glycosylated siglec6 expression in syncytiotrophoblast-derived extracellular vesicles from preeclamptic placentas |
| title_full_unstemmed | Glycosylated siglec6 expression in syncytiotrophoblast-derived extracellular vesicles from preeclamptic placentas |
| title_short | Glycosylated siglec6 expression in syncytiotrophoblast-derived extracellular vesicles from preeclamptic placentas |
| title_sort | glycosylated siglec6 expression in syncytiotrophoblast derived extracellular vesicles from preeclamptic placentas |
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