Second eye of patients with unilateral neovascular age-related macular degeneration: Caucasians vs Chinese.
PURPOSE: To investigate the correlation between morphological features of choroidal neovascularisation (CNV) secondary to age-related macular degeneration (AMD) in the first eye and the severity of age-related maculopathy (ARM) in the fellow eyes in two racial groups: Caucasians and Chinese. PARTICI...
| Main Authors: | , , , , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2006
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| _version_ | 1797087141297127424 |
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| author | Sivaprasad, S Membrey, W Sivagnanavel, V Gonzalez, J Liu, D Chan, WM Lam, D Jackson, H Chong, N |
| author_facet | Sivaprasad, S Membrey, W Sivagnanavel, V Gonzalez, J Liu, D Chan, WM Lam, D Jackson, H Chong, N |
| author_sort | Sivaprasad, S |
| collection | OXFORD |
| description | PURPOSE: To investigate the correlation between morphological features of choroidal neovascularisation (CNV) secondary to age-related macular degeneration (AMD) in the first eye and the severity of age-related maculopathy (ARM) in the fellow eyes in two racial groups: Caucasians and Chinese. PARTICIPANTS: A total of 135, fluorescein angiograms of patients with unilateral neovascular AMD and ARM in the fellow eyes were included in the study: 38 Caucasians from King's College Hospital, UK; 45 Caucasians from West Kent Eye Centre, UK; 52 Chinese from Hong Kong Eye Hospital, Hong Kong. MAIN OUTCOME MEASURES: CNV subtype in the affected eye and ARM severity in the second eyes. RESULTS: Although the proportion of CNV subtypes in the three groups were similar, the Chinese cohort showed significantly less ARM severity compared to the Caucasian cohorts (P < 0.05). CONCLUSION: Although drusen and retinal pigmentary changes may be prognostic indicators of CNV, this study suggest that other factors contribute significantly to the pathogenesis of CNV in AMD. |
| first_indexed | 2024-03-07T02:31:47Z |
| format | Journal article |
| id | oxford-uuid:a77ba364-9684-427e-83a8-b744c27c8949 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:31:47Z |
| publishDate | 2006 |
| record_format | dspace |
| spelling | oxford-uuid:a77ba364-9684-427e-83a8-b744c27c89492022-03-27T02:54:55ZSecond eye of patients with unilateral neovascular age-related macular degeneration: Caucasians vs Chinese.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a77ba364-9684-427e-83a8-b744c27c8949EnglishSymplectic Elements at Oxford2006Sivaprasad, SMembrey, WSivagnanavel, VGonzalez, JLiu, DChan, WMLam, DJackson, HChong, NPURPOSE: To investigate the correlation between morphological features of choroidal neovascularisation (CNV) secondary to age-related macular degeneration (AMD) in the first eye and the severity of age-related maculopathy (ARM) in the fellow eyes in two racial groups: Caucasians and Chinese. PARTICIPANTS: A total of 135, fluorescein angiograms of patients with unilateral neovascular AMD and ARM in the fellow eyes were included in the study: 38 Caucasians from King's College Hospital, UK; 45 Caucasians from West Kent Eye Centre, UK; 52 Chinese from Hong Kong Eye Hospital, Hong Kong. MAIN OUTCOME MEASURES: CNV subtype in the affected eye and ARM severity in the second eyes. RESULTS: Although the proportion of CNV subtypes in the three groups were similar, the Chinese cohort showed significantly less ARM severity compared to the Caucasian cohorts (P < 0.05). CONCLUSION: Although drusen and retinal pigmentary changes may be prognostic indicators of CNV, this study suggest that other factors contribute significantly to the pathogenesis of CNV in AMD. |
| spellingShingle | Sivaprasad, S Membrey, W Sivagnanavel, V Gonzalez, J Liu, D Chan, WM Lam, D Jackson, H Chong, N Second eye of patients with unilateral neovascular age-related macular degeneration: Caucasians vs Chinese. |
| title | Second eye of patients with unilateral neovascular age-related macular degeneration: Caucasians vs Chinese. |
| title_full | Second eye of patients with unilateral neovascular age-related macular degeneration: Caucasians vs Chinese. |
| title_fullStr | Second eye of patients with unilateral neovascular age-related macular degeneration: Caucasians vs Chinese. |
| title_full_unstemmed | Second eye of patients with unilateral neovascular age-related macular degeneration: Caucasians vs Chinese. |
| title_short | Second eye of patients with unilateral neovascular age-related macular degeneration: Caucasians vs Chinese. |
| title_sort | second eye of patients with unilateral neovascular age related macular degeneration caucasians vs chinese |
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