The impact of rare variation on gene expression across tissues

The impact of rare variation on gene expression across tissues

Rare genetic variants are abundant in humans and are expected to contribute to individual disease risk. While genetic association studies have successfully identified common genetic variants associated with susceptibility, these studies are not practical for identifying rare variants. Efforts to dis...

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Bibliografiske detaljer
Main Authors:	Li, X, Kim, Y, Tsang, EK, Davis, JR, Damani, FN, Chiang, C, Hess, GT, Zappala, Z, Strober, BJ, Scott, AJ, Li, A, Ganna, A, Bassik, MC, Merker, JD, Hall, IM, Battle, A, Montgomery, SB, McCarthy, MI, Payne, AJ
Format:	Journal article
Sprog:	English
Udgivet:	Nature Publishing Group 2017

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Udgivet: (2017)

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af: 190378 Battle, Guy, et al.
Udgivet: (2001)

O and H isotopic evidence for a mantle source of water in appinite magma: An example from the late Neoproterozoic Greendale Complex, Nova Scotia
af: Cawood, IP, et al.
Udgivet: (2021)

Analysis of two different tandem repetitive elements within the human apolipoprotein B gene.
af: EH Ludwig, et al.
Udgivet: (1991-02-01)

Two centuries of immunisation in the UK (part II)
af: Lang, S, et al.
Udgivet: (2019)

The relationship between leadership and physician well-being: a scoping review
af: Montgomery AJ
Udgivet: (2016-10-01)

Object Reconstruction From Fourier Magnitude Information Only
af: A.J. Tawfiq, et al.
Udgivet: (2017-05-01)

Plasmodium vivax controlled human malaria infection - Progress and prospects.
af: Payne, R, et al.
Udgivet: (2016)

Mechanisms of NKG2D ligand regulation
af: McCarthy, M, et al.
Udgivet: (2013)

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af: Mary McCarthy, et al.
Udgivet: (2011-01-01)

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af: H.R. McCarthy, et al.
Udgivet: (2024-05-01)

Autocad express /
af: 465379 McCarthy, Tim, et al.
Udgivet: (1992)

Value of hospital anticoagulation stewardship programme: A systematic review
af: V. Silvari, et al.
Udgivet: (2024-03-01)

Portfolio democracy
af: Michael A. McCarthy
Udgivet: (2024-08-01)

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af: Lauren A. McCarthy
Udgivet: (2018-04-01)

Transaction Costs: Prosecuting child trafficking for illegal adoption in Russia
af: Lauren A McCarthy
Udgivet: (2016-05-01)

Reinventory of the vascular plants of Mormon Island Crane Meadows after forty years of restoration, invasion, and climate change
af: A.J. Caven, et al.
Udgivet: (2022-06-01)

Pharmacological interventions for ADHD: how do adolescent and adult patient beliefs and attitudes impact treatment adherence?
af: McCarthy S
Udgivet: (2014-09-01)

Exploring a Potential Interaction Between the Effect of Specific Maternal Smoking Patterns and Comorbid Antenatal Depression in Causing Postpartum Depression
af: Kondracki AJ, et al.
Udgivet: (2024-04-01)

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af: 465039 McCarthy, Bernice, et al.
Udgivet: (2006)

A multi-tissue transcriptome analysis of human metabolites guides interpretability of associations based on multi-SNP models for gene expression
af: Ndungu, A, et al.
Udgivet: (2020)

Hypervariability in a minisatellite 3' of the apolipoprotein B gene in patients with coronary heart disease compared with normal controls.
af: W Friedl, et al.
Udgivet: (1990-04-01)

The Influence of Composition and Manufacturing Approach on the Physical and Rehydration Properties of Milk Protein Concentrate Powders
af: David J. McSweeney, et al.
Udgivet: (2020-02-01)

Getting it right this time : how to create a loving and lasting marriage /
af: McCarthy, Barry W., 1943-, et al.
Udgivet: (2006)

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af: M. Henchion, et al.
Udgivet: (2021-05-01)

Variation across the allele frequency spectrum.
af: Gloyn, A, et al.
Udgivet: (2010)

The genetics of type 2 diabetes and its clinical relevance.
af: Pal, A, et al.
Udgivet: (2013)

Genetics for Endocrinologists: The Molecular Genetic Basis of Endocrine Disorders.
af: McCarthy, M, et al.
Udgivet: (2003)

The genetics of type 2 diabetes.
af: Gloyn, A, et al.
Udgivet: (2001)

What makes a good genetic association study?
af: Hattersley, A, et al.
Udgivet: (2005)

Preface
af: Gloyn, A, et al.
Udgivet: (2014)

Language-related field potentials in the anterior-medial temporal lobe: II. Effects of word type and semantic priming.
af: Nobre, A, et al.
Udgivet: (1995)

Learning from molecular genetics: novel insights arising from the definition of genes for monogenic and type 2 diabetes.
af: McCarthy, M, et al.
Udgivet: (2008)

Modulation of semantic processing by spatial selective attention.
af: McCarthy, G, et al.
Udgivet: (1993)

What makes a good genetic association study?
af: Hattersley, A, et al.
Udgivet: (2005)

Language-Related ERPs: Scalp Distributions and Modulation by Word Type and Semantic Priming.
af: Nobre, A, et al.
Udgivet: (1994)

The value of genetic risk scores in precision medicine for diabetes
af: McCarthy, M, et al.
Udgivet: (2018)

Change trends in urban freight delivery: a qualitative inquiry
af: Hopkins, D, et al.
Udgivet: (2016)

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af: Gloyn, A, et al.
Udgivet: (2008)

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af: 244822 McCarthy, Michael A.
Udgivet: (2007)