Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas.
Clear-cut inherited Mendelian traits, such as familial adenomatous polyposis or hereditary nonpolyposis colorectal cancer, account for <4% of colorectal cancers. Another 20% of all colorectal cancers are thought to occur in individuals with a significant inherited multifactorial susceptibilit...
主要な著者: | Fearnhead, N, Wilding, J, Winney, B, Tonks, S, Bartlett, S, Bicknell, D, Tomlinson, I, Mortensen, N, Bodmer, W |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
2004
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