Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas.

Multiple rare variants in different genes account for multifactorial inherited susceptibility to colorectal adenomas.

Clear-cut inherited Mendelian traits, such as familial adenomatous polyposis or hereditary nonpolyposis colorectal cancer, account for <4% of colorectal cancers. Another 20% of all colorectal cancers are thought to occur in individuals with a significant inherited multifactorial susceptibilit...

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Bibliografiska uppgifter
Huvudupphovsmän:	Fearnhead, N, Wilding, J, Winney, B, Tonks, S, Bartlett, S, Bicknell, D, Tomlinson, I, Mortensen, N, Bodmer, W
Materialtyp:	Journal article
Språk:	English
Publicerad:	2004

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