Genetic testing is important in families with a history suggestive of hereditary non-polyposis colorectal cancer even if the Amsterdam criteria are not fulfilled.

BACKGROUND: Clinical screening is still the first-line approach to identification of families with hereditary non-polyposis colorectal cancer (HNPCC). The need for uniformity of diagnosis of the syndrome, particularly in multicentre studies, led to the establishment of a set of minimum diagnostic cr...

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Bibliographic Details
Main Authors: Beck, N, Tomlinson, I, Homfray, T, Hodgson, S, Harocopos, C, Bodmer, W
Format: Journal article
Language:English
Published: 1997