Functional epistasis on a common MHC haplotype associated with multiple sclerosis.

Functional epistasis on a common MHC haplotype associated with multiple sclerosis.

Genes in the major histocompatibility complex (MHC) encode proteins important in activating antigen-specific immune responses. Alleles at adjacent MHC loci are often in strong linkage disequilibrium; however, little is known about the mechanisms responsible for this linkage disequilibrium. Here we r...

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Dettagli Bibliografici
Autori principali:	Gregersen, J, Kranc, K, Ke, X, Svendsen, P, Madsen, L, Thomsen, A, Cardon, L, Bell, J, Fugger, L
Natura:	Journal article
Lingua:	English
Pubblicazione:	2006

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