Functional epistasis on a common MHC haplotype associated with multiple sclerosis.
Genes in the major histocompatibility complex (MHC) encode proteins important in activating antigen-specific immune responses. Alleles at adjacent MHC loci are often in strong linkage disequilibrium; however, little is known about the mechanisms responsible for this linkage disequilibrium. Here we r...
| Auteurs principaux: | , , , , , , , , |
|---|---|
| Format: | Journal article |
| Langue: | English |
| Publié: |
2006
|