Study protocol for a randomised controlled double-blinded trial of the dose-dependent efficacy and safety of primaquine for clearance of gametocytes in children with uncomplicated falciparum malaria in Uganda

Study protocol for a randomised controlled double-blinded trial of the dose-dependent efficacy and safety of primaquine for clearance of gametocytes in children with uncomplicated falciparum malaria in Uganda

Objectives: For the purpose of blocking transmission of Plasmodium falciparum malaria from humans to mosquitoes, a single dose of primaquine is recommended by theWHO as an addition to artemisinin combination therapy. Primaquine clears gametocytes but causes dose-dependent haemolysis in individuals w...

Полное описание

Библиографические подробности
Главные авторы:	Eziefula, A, Staedke, S, Yeung, S, Webb, E, Kamya, M, White, N, Bousema, T, Drakeley, C
Формат:	Journal article
Язык:	English
Опубликовано:	BMJ Publishing Group 2013

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