Study protocol for a randomised controlled double-blinded trial of the dose-dependent efficacy and safety of primaquine for clearance of gametocytes in children with uncomplicated falciparum malaria in Uganda

Objectives: For the purpose of blocking transmission of Plasmodium falciparum malaria from humans to mosquitoes, a single dose of primaquine is recommended by theWHO as an addition to artemisinin combination therapy. Primaquine clears gametocytes but causes dose-dependent haemolysis in individuals w...

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Príomhchruthaitheoirí: Eziefula, A, Staedke, S, Yeung, S, Webb, E, Kamya, M, White, N, Bousema, T, Drakeley, C
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: BMJ Publishing Group 2013