Reduction of chemokine levels and leukocyte traffic to joints by tumor necrosis factor alpha blockade in patients with rheumatoid arthritis.

OBJECTIVE: To verify the hypothesis that in rheumatoid arthritis (RA), tumor necrosis factor alpha (TNFalpha) plays a critical role in regulating leukocyte trafficking and chemokine levels. METHODS: Ten patients with longstanding RA received a single 10 mg/kg infusion of anti-TNFalpha monoclonal ant...

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Những tác giả chính: Taylor, P, Peters, A, Paleolog, E, Chapman, P, Elliott, M, McCloskey, R, Feldmann, M, Maini, R
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2000