Simulation-based inference for global health decisions

The COVID-19 pandemic has highlighted the importance of in-silico epidemiological modelling in predicting the dynamics of infectious diseases to inform health policy and decision makers about suitable prevention and containment strategies. Work in this setting involves solving challenging inference...

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Main Authors: Schroeder de Witt, C, Gram-Hansen, B, Nardelli, N, Gambardella, A, Zinkov, R, Dokania, P, Siddharth, N, Espinosa-Gonzalez, AB, Darzi, A, Torr, PHS, Güneş Baydin, A
Format: Conference item
Language:English
Published: 2020
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author Schroeder de Witt, C
Gram-Hansen, B
Nardelli, N
Gambardella, A
Zinkov, R
Dokania, P
Siddharth, N
Espinosa-Gonzalez, AB
Darzi, A
Torr, PHS
Güneş Baydin, A
author_facet Schroeder de Witt, C
Gram-Hansen, B
Nardelli, N
Gambardella, A
Zinkov, R
Dokania, P
Siddharth, N
Espinosa-Gonzalez, AB
Darzi, A
Torr, PHS
Güneş Baydin, A
author_sort Schroeder de Witt, C
collection OXFORD
description The COVID-19 pandemic has highlighted the importance of in-silico epidemiological modelling in predicting the dynamics of infectious diseases to inform health policy and decision makers about suitable prevention and containment strategies. Work in this setting involves solving challenging inference and control problems in individual-based models of ever increasing complexity. Here we discuss recent breakthroughs in machine learning, specifically in simulation-based inference, and explore its potential as a novel venue for model calibration to support the design and evaluation of public health interventions. To further stimulate research, we are developing software interfaces that turn two cornerstone COVID-19 and malaria epidemiology models (CovidSim and OpenMalaria) into probabilistic programs, enabling efficient interpretable Bayesian inference within those simulators.
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spelling oxford-uuid:a7f1c1d8-4f38-4794-8767-632d9f1ccff32024-04-26T11:16:31ZSimulation-based inference for global health decisionsConference itemhttp://purl.org/coar/resource_type/c_6670uuid:a7f1c1d8-4f38-4794-8767-632d9f1ccff3EnglishSymplectic Elements2020Schroeder de Witt, CGram-Hansen, BNardelli, NGambardella, AZinkov, RDokania, PSiddharth, NEspinosa-Gonzalez, ABDarzi, ATorr, PHSGüneş Baydin, AThe COVID-19 pandemic has highlighted the importance of in-silico epidemiological modelling in predicting the dynamics of infectious diseases to inform health policy and decision makers about suitable prevention and containment strategies. Work in this setting involves solving challenging inference and control problems in individual-based models of ever increasing complexity. Here we discuss recent breakthroughs in machine learning, specifically in simulation-based inference, and explore its potential as a novel venue for model calibration to support the design and evaluation of public health interventions. To further stimulate research, we are developing software interfaces that turn two cornerstone COVID-19 and malaria epidemiology models (CovidSim and OpenMalaria) into probabilistic programs, enabling efficient interpretable Bayesian inference within those simulators.
spellingShingle Schroeder de Witt, C
Gram-Hansen, B
Nardelli, N
Gambardella, A
Zinkov, R
Dokania, P
Siddharth, N
Espinosa-Gonzalez, AB
Darzi, A
Torr, PHS
Güneş Baydin, A
Simulation-based inference for global health decisions
title Simulation-based inference for global health decisions
title_full Simulation-based inference for global health decisions
title_fullStr Simulation-based inference for global health decisions
title_full_unstemmed Simulation-based inference for global health decisions
title_short Simulation-based inference for global health decisions
title_sort simulation based inference for global health decisions
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AT siddharthn simulationbasedinferenceforglobalhealthdecisions
AT espinosagonzalezab simulationbasedinferenceforglobalhealthdecisions
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