Genotyping technologies for all
Three and a half million single nucleotide polymorphisms are now publicly available through the International HapMap project, enabling genetic and pharmacogenetic studies involving whole genome or comprehensive candidate gene association approaches. The cost/genotype for these studies has been drive...
| Main Author: | |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2006
|
| _version_ | 1797087258711425024 |
|---|---|
| author | Ragoussis, J |
| author_facet | Ragoussis, J |
| author_sort | Ragoussis, J |
| collection | OXFORD |
| description | Three and a half million single nucleotide polymorphisms are now publicly available through the International HapMap project, enabling genetic and pharmacogenetic studies involving whole genome or comprehensive candidate gene association approaches. The cost/genotype for these studies has been driven down to levels unimagined only a few years ago albeit under particular conditions. Here, eight commonly used commercially available genotyping assays (TaqMan, SNPstream, SNPlex, hME/iPLEX, MIP, GenChip, Goldengate, Infinium I and II) are briefly presented and their particular strengths and weaknesses as well as their suitability for particular types of studies and the related costs are also discussed. © 2006 Elsevier Ltd. All rights reserved. |
| first_indexed | 2024-03-07T02:33:16Z |
| format | Journal article |
| id | oxford-uuid:a7f1e6c2-211f-41c9-a153-51f839e0e4c8 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:33:16Z |
| publishDate | 2006 |
| record_format | dspace |
| spelling | oxford-uuid:a7f1e6c2-211f-41c9-a153-51f839e0e4c82022-03-27T02:57:55ZGenotyping technologies for allJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a7f1e6c2-211f-41c9-a153-51f839e0e4c8EnglishSymplectic Elements at Oxford2006Ragoussis, JThree and a half million single nucleotide polymorphisms are now publicly available through the International HapMap project, enabling genetic and pharmacogenetic studies involving whole genome or comprehensive candidate gene association approaches. The cost/genotype for these studies has been driven down to levels unimagined only a few years ago albeit under particular conditions. Here, eight commonly used commercially available genotyping assays (TaqMan, SNPstream, SNPlex, hME/iPLEX, MIP, GenChip, Goldengate, Infinium I and II) are briefly presented and their particular strengths and weaknesses as well as their suitability for particular types of studies and the related costs are also discussed. © 2006 Elsevier Ltd. All rights reserved. |
| spellingShingle | Ragoussis, J Genotyping technologies for all |
| title | Genotyping technologies for all |
| title_full | Genotyping technologies for all |
| title_fullStr | Genotyping technologies for all |
| title_full_unstemmed | Genotyping technologies for all |
| title_short | Genotyping technologies for all |
| title_sort | genotyping technologies for all |
| work_keys_str_mv | AT ragoussisj genotypingtechnologiesforall |