Hepcidin is suppressed by erythropoiesis in hemoglobin E β-thalassemia and β-thalassemia trait.
HbE β-thalassemia is the most common severe thalassemia syndrome across Asia, and millions are carriers. Clinical heterogeneity in HbE β-thalassemia is incompletely explained by genotype, and the interaction of phenotypic variation with hepcidin is unknown. The effect of thalassemia carriage on hepc...
Auteurs principaux: | Jones, E, Pasricha, SR, Allen, A, Evans, P, Fisher, C, Wray, K, Premawardhena, A, Bandara, D, Perera, A, Webster, C, Sturges, P, Olivieri, N, St Pierre, T, Armitage, A, Porter, J, Weatherall, D, Drakesmith, H |
---|---|
Format: | Journal article |
Langue: | English |
Publié: |
2014
|
Documents similaires
-
Differences in the erythropoiesis-hepcidin-iron store axis between hemoglobin H disease and β-thalassemia intermedia
par: Raffaella Origa, et autres
Publié: (2015-05-01) -
Ineffective Erythropoiesis in β-Thalassemia
par: Jean-Antoine Ribeil, et autres
Publié: (2013-01-01) -
Adaptation to anemia in hemoglobin E-β thalassemia (Blood (2010) 116, 24 (5368-5370))
par: Allen, A, et autres
Publié: (2011) -
Challenging the Erythropoiesis Paradigm in β-Thalassemia
par: Francesca Vinchi, et autres
Publié: (2020-10-01) -
Adaptation to anemia in hemoglobin E-ß thalassemia.
par: Allen, A, et autres
Publié: (2010)