Stereoselectivity in the birch reduction of 2-furoic acid derivatives
The preparation and Birch reduction of chiral 3-methyl-2-furoic acid derivatives is described. Using a Ca symmetrical amine as a chiral auxiliary, very high levels of sterochemical control could be obtained. Moreover, the auxiliary could be removed conveniently by heating in 6M HCl to liberate a car...
Autores principales: | Donohoe, T, Helliwell, M, Stevenson, C, Ladduwahetty, T |
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Formato: | Journal article |
Lenguaje: | English |
Publicado: |
1998
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