Low-level microsatellite instability occurs in most colorectal cancers and is a nonrandomly distributed quantitative trait.

About 10-15% of colorectal cancers show high-level microsatellite instability. The characteristics and very existence of low-level instability (MSI-L) are unclear, although some studies have found associations between MSI-L and molecular characteristics, notably more frequent K-ras mutations and a l...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Halford, S, Sasieni, P, Rowan, A, Wasan, H, Bodmer, W, Talbot, I, Hawkins, N, Ward, R, Tomlinson, I
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2002