Serotonin modulates behavioral reactions to unfairness.
Serotonin (5-HT) has long been implicated in social behavior and impulsivity, but the mechanisms through which it modulates self-control remain unclear. We observed the effects of manipulating 5-HT function on behavior in the ultimatum game, where players must decide whether to accept or reject fair...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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| _version_ | 1797087268539727872 |
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| author | Crockett, M Clark, L Tabibnia, G Lieberman, MD Robbins, T |
| author_facet | Crockett, M Clark, L Tabibnia, G Lieberman, MD Robbins, T |
| author_sort | Crockett, M |
| collection | OXFORD |
| description | Serotonin (5-HT) has long been implicated in social behavior and impulsivity, but the mechanisms through which it modulates self-control remain unclear. We observed the effects of manipulating 5-HT function on behavior in the ultimatum game, where players must decide whether to accept or reject fair or unfair monetary offers from another player. Participants with depleted 5-HT levels rejected a greater proportion of unfair offers, but not fair offers, without showing changes in mood, fairness judgment, basic reward processing, or response inhibition. Our results suggest that 5-HT plays a critical role in regulating emotion during social decision-making. |
| first_indexed | 2024-03-07T02:33:25Z |
| format | Journal article |
| id | oxford-uuid:a8002429-fb31-4138-86ad-d0d091b59129 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T02:33:25Z |
| publishDate | 2008 |
| record_format | dspace |
| spelling | oxford-uuid:a8002429-fb31-4138-86ad-d0d091b591292022-03-27T02:58:19ZSerotonin modulates behavioral reactions to unfairness.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:a8002429-fb31-4138-86ad-d0d091b59129EnglishSymplectic Elements at Oxford2008Crockett, MClark, LTabibnia, GLieberman, MDRobbins, TSerotonin (5-HT) has long been implicated in social behavior and impulsivity, but the mechanisms through which it modulates self-control remain unclear. We observed the effects of manipulating 5-HT function on behavior in the ultimatum game, where players must decide whether to accept or reject fair or unfair monetary offers from another player. Participants with depleted 5-HT levels rejected a greater proportion of unfair offers, but not fair offers, without showing changes in mood, fairness judgment, basic reward processing, or response inhibition. Our results suggest that 5-HT plays a critical role in regulating emotion during social decision-making. |
| spellingShingle | Crockett, M Clark, L Tabibnia, G Lieberman, MD Robbins, T Serotonin modulates behavioral reactions to unfairness. |
| title | Serotonin modulates behavioral reactions to unfairness. |
| title_full | Serotonin modulates behavioral reactions to unfairness. |
| title_fullStr | Serotonin modulates behavioral reactions to unfairness. |
| title_full_unstemmed | Serotonin modulates behavioral reactions to unfairness. |
| title_short | Serotonin modulates behavioral reactions to unfairness. |
| title_sort | serotonin modulates behavioral reactions to unfairness |
| work_keys_str_mv | AT crockettm serotoninmodulatesbehavioralreactionstounfairness AT clarkl serotoninmodulatesbehavioralreactionstounfairness AT tabibniag serotoninmodulatesbehavioralreactionstounfairness AT liebermanmd serotoninmodulatesbehavioralreactionstounfairness AT robbinst serotoninmodulatesbehavioralreactionstounfairness |