Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes.

Epidemiological studies consistently show that circulating sex hormone binding globulin (SHBG) levels are lower in type 2 diabetes patients than non-diabetic individuals, but the causal nature of this association is controversial. Genetic studies can help dissect causal directions of epidemiological...

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Bibliographic Details
Main Authors: Perry, JR, Weedon, M, Langenberg, C, Jackson, A, Lyssenko, V, Sparsø, T, Thorleifsson, G, Grallert, H, Ferrucci, L, Maggio, M, Paolisso, G, Walker, M, Palmer, C, Payne, F, Young, E, Herder, C, Narisu, N, Morken, M, Bonnycastle, L, Owen, K, Shields, B, Knight, B, Bennett, A, Groves, C, Ruokonen, A
Format: Journal article
Language:English
Published: 2010